Two Cases of Fatal Zopiclone Overdose

Two cases of fatal zopiclone overdose.

Two cases of death due to the ingestion of zopiclone are presented. Quantitative determinations of zopiclone yielded 1.4-3.9 mg/L in the blood, 0.81 and 8.7 mg/kg in the liver, and 13.5 and 133 mg in the stomach contents. Drug concentrations were interpreted relative to the case findings, published data, and a limited evaluation of therapeutic concentrations found in two cases of therapeutic zo...

Fatal digoxin overdose.

Overdosage with cardiac glycosides is well documented, but not usually fatal. A case is described in which cardiac arrest in asystole was associated with a serum digoxin level of 50-4 microgram/1, the highest concentration yet reported after oral administration.

Non-Fatal Amlodipine and Insulin Overdose in an Elderly Person

Prevention of fatal opioid overdose.

OPIOID OVERDOSE IS A BURGEONING PUBLIC HEALTH crisis, accounting for at least 16 000 deaths annually in the United States. Opioid overdose occurs across sex, ethnic, age, and geographic strata and involvesbothmedicalandnonmedicalopioiduse.Todate, federal government response has focused primarily on monitoringandsecuringthedrugsupply. ThisViewpointsuggestsvariousstepsnecessarytosupportamorecompr...

Two fatal cases of septicaemia due to

Langford and Hansen (1954) have suggested that the genus Erysipelothrix possesses a single species Erysipelothrix insidiosa and that subdivision into further species is not justified; following their terminology E. insidiosa and E. rhusiopathiae in this account are considered synonymous. Erysipelothrix rhusiopathiae is recognized as the pathogen causing the skin lesions of human erysipeloid. Th...